Recombinant retroviral vector interferes with the detection of amphotropic replication competent retrovirus in standard culture assays
This paper has been cited over 40 times. It summarizes studies that revealed that recombinant retroviral vector can interfere with the detection of low-level RCR in culture and that such interference can be partially overcome by culturing the vector preparation with a permissive cell line for several days before testing on the indicator cell line.