This paper summarizes work to character vector immunogenicity. Studies showed that intramuscular (i.m.) administration of retroviral vector induces strong anti-vector Ig responses, in a dose-dependent fashion. Although such anti-vector Ig was capable of neutralizing vector in an in vitro assay, no adverse effect on vector efficacy was seen following repeated i.m. administration.
https://sajjadiconsulting.com/wp-content/uploads/2020/01/publicationsblog.jpg 1440 1920 email@example.com https://sajjadiconsulting.com/wp-content/uploads/2021/08/sajjadi-logo-web.png firstname.lastname@example.org 15:29:512021-09-28 09:26:35Anti-vector immunoglobulin induced by retroviral vectors